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Study details
Enrolling now

Defibrotide for Sickle Cell Disease Patients Undergoing Stem Cell Transplant

New York Medical College
NCT IDNCT02675959ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

40

Study length

about 11 years

Ages

0.5–34

Locations

4 sites in CA, FL, NY +1

About this study

This trial is testing the safety and effectiveness of giving Defibrotide to adults and children with sickle cell disease who are undergoing a stem cell transplant. The goal is to see if this treatment helps prevent or treat sinusoidal obstructive syndrome (SOS), a serious complication after the transplant.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Defibrotide
PhasePhase 2
DrugDefibrotide

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

defibrotide