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Study details
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Blinatumomab, Inotuzumab Ozogamicin, and Chemotherapy for Acute Lymphoblastic Leukemia

M.D. Anderson Cancer Center
NCT IDNCT02877303ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

80

Study length

about 10 years

Ages

14+

Locations

1 site in TX

About this study

This trial is testing if blinatumomab, inotuzumab ozogamicin, and combination chemotherapy are effective as the first treatment for patients with B acute lymphoblastic leukemia. This new approach may offer a better chance of success than standard chemotherapy alone.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Laboratory Biomarker Analysis
  • 2.Receive Blinatumomab
  • 3.Receive Inotuzumab Ozogamicin
  • +3 more
PhasePhase 2
DrugBlinatumomab
Routeinjection
Primary goalRelapse-free survival (RFS)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

blinatumomab, cyclophosphamide (Alkylating chemotherapy; crosslinks DNA strands), cytarabine, dexamethasone, Antineoplastic Agent [TC] (Topoisomerase 2 Inhibitors), inotuzumab ozogamicin, mercaptopurine, methotrexate

Drug routes

injection, intravenous, infusion, injection (Injection), ocular, oral (Oral Tablet), oral

Endpoints

Primary: Relapse-free survival (RFS)

Secondary: Incidence of adverse events, Overall response rate, Overall survival

Body systems

Oncology