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Study details
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Vascular Function in Health and Disease

Russell Richardson
NCT IDNCT02966665ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

420

Study length

about 18 years

Ages

18+

Locations

1 site in UT

About this study

This trial is testing how vascular function changes with age and in people with certain diseases like COPD, heart disease, and high blood pressure. The goal is to understand why these changes happen and if they can be fixed.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Angiotensin-II, Valsartan
  • 2.Maximum Exercise Tests
  • 3.Take Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine
  • +3 more
PhasePhase 1
DrugAcetylcholine
Routeinjection

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

acetylcholine, Cardiovascular Agent [TC] (Unknown Cellular or Molecular Interaction), angiotensin II, supplement (Vitamin; antioxidant), dietary supplement, fexofenadine, RESPIRATORY SYSTEM, norepinephrine

Drug routes

injection (Injection), oral (Oral Capsule), oral (Oral Tablet), ocular (Ophthalmic Solution), injection

Endpoints

Secondary: Change in Blood Pressure

Body systems

Cardiology / Heart, Respiratory