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Study details
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A Prospective, Randomized, Open Label Trial of Two Doses of Oral Betaine

Southern California Institute for Research and Education
NCT IDNCT03073343ClinicalTrials.gov data as of Apr 2026
Target enrollment

48

Study length

about 12 years

Ages

18–75

Locations

1 site in CA

About this study

This trial is testing two different doses of oral betaine to see if it helps with liver problems. Patients will take the betaine as a powder mixed in water and drink it daily for 4431 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Betaine (trimethyglycine)
DrugBetaine (trimethyglycine)
Routeoral
Primary goalChange in alanine aminotransferase (ALT) level in all study participants

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

betaine

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Change in alanine aminotransferase (ALT) level in all study participants

Secondary: Compare changes in alanine aminotransferase (ALT) level in both cohorts

Body systems

Endocrinology