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Study details
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Combination Chemotherapy for Relapsed/Refractory Blood Cancers

M.D. Anderson Cancer Center
NCT IDNCT03136146ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

42

Study length

about 10 years

Ages

15+

Locations

1 site in TX

About this study

This trial is testing a combination of chemotherapy drugs to see if it works in people with certain types of blood cancers that have returned or not responded to previous treatment. The treatment includes medications like clofarabine, etoposide, and bortezomib, which work by killing cancer cells or stopping them from growing.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Ofatumumab
  • 2.Receive Pegfilgrastim
  • 3.Receive Rituximab
  • +3 more
PhasePhase 2
DrugBortezomib
Routeinjection
Primary goalIncidence of adverse events

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

bortezomib, clofarabine, cyclophosphamide (Alkylating chemotherapy; crosslinks DNA strands), dexamethasone, etoposide, ofatumumab, pegfilgrastim, rituximab (Monoclonal antibody; targets CD20 on B-cells to destroy them)

Drug routes

injection (Injection), injection, intravenous, infusion, ocular

Endpoints

Primary: Incidence of adverse events, Overall response rate (ORR) (Phase II)

Secondary: Event free survival, Overall survival

Body systems

Oncology