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Study details
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Gene Transfer Trial for Cancer

National Cancer Institute (NCI)
NCT IDNCT03190941ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

110

Study length

about 11 years

Ages

18–72

Locations

1 site in MD

About this study

This trial is testing a new treatment that involves taking white blood cells from your body, modifying them in the lab with a special gene, and then returning them to you. The goal is to determine if this modified cell therapy is safe and can shrink tumors in people with certain types of cancer.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Anti-KRAS G12V mTCR PBL
  • 2.Take Aldesleukin
  • 3.Take Cyclophosphamide
  • +1 more
PhasePhase 1/Phase 2
DrugAldesleukin
Primary goalFrequency and severity of treatment-related adverse events

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

aldesleukin, cyclophosphamide (Alkylating chemotherapy; crosslinks DNA strands), fludarabine

Drug routes

infusion

Endpoints

Primary: Frequency and severity of treatment-related adverse events, Response rate

Body systems

Oncology