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Study details
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Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

M.D. Anderson Cancer Center
NCT IDNCT03383575ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

63

Study length

about 9.1 years

Ages

12+

Locations

3 sites in MD, OH, TX

About this study

This trial is testing azacitidine and enasidenib as a treatment for patients with IDH2-mutant myelodysplastic syndrome. The goal is to assess the safety and effectiveness of these medications in stopping cancer cell growth.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Quality-of-Life Assessment
  • 2.Take Azacitidine
  • 3.Take Enasidenib
PhasePhase 2
DrugAzacitidine
Routeinjection
Primary goalIncidence of adverse events

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

azacitidine, enasidenib

Drug routes

injection, subcutaneous, oral (Oral Tablet)

Endpoints

Primary: Incidence of adverse events, Overall response rate

Secondary: Event-free survival (EFS), Overall survival (OS)

Body systems

Musculoskeletal, Oncology