Skip to content
Study details
Enrolling now

Gene Therapy Trial for Cancer

National Cancer Institute (NCI)
NCT IDNCT03412877ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

285

Study length

about 9.6 years

Ages

18–72

Locations

1 site in MD

About this study

This trial is testing a new treatment that involves genetically engineering your own T-cells to fight cancer. It's being done in people whose cancer hasn't responded to standard treatments. The goal is to see if gene therapy can shrink tumors.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Individual Patient TCR-Transduced PBL
  • 2.Take Aldesleukin
  • 3.Take Cyclophosphamide
  • +2 more
PhasePhase 2
DrugAldesleukin
Primary goalResponse rate

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

aldesleukin, cyclophosphamide (Alkylating chemotherapy; crosslinks DNA strands), fludarabine, immunotherapy (PD-1 inhibitor immunotherapy (pembrolizumab)), pembrolizumab (Immune checkpoint inhibitor; blocks PD-1 to boost T-cell attack on cancer)

Drug routes

infusion

Endpoints

Primary: Response rate

Body systems

Endocrinology, Oncology