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Study details
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The Venous Distension Reflex and Orthostatic Hypertension

Milton S. Hershey Medical Center
NCT IDNCT03496792ClinicalTrials.gov data as of Apr 2026
Target enrollment

30

Study length

about 6.2 years

Ages

18+

Locations

1 site in PA

About this study

Researchers are testing whether distending veins in legs causes a rise in blood pressure (orthostatic hypertension). The trial will compare different methods of vein distention, including limb occlusion with negative pressure, limb occlusion without negative pressure, tilt with external pressure, and tilt without external pressure. The goal is to understand how this venous distension reflex affects blood pressure responses to stress.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Limb occlusion + negative pressure
  • 2.Limb occlusion + no negative pressure
  • 3.Tilt + external pressure
  • +1 more

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Blood pressure in mmHg, Heart rate in beats per minute