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Study details
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iExosomes for Pancreatic Cancer

M.D. Anderson Cancer Center
NCT IDNCT03608631ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

28

Study length

about 6.3 years

Ages

18+

Locations

1 site in TX

About this study

This trial is testing a new treatment, iExosomes, in people with metastatic pancreas cancer that has a KrasG12D mutation. The goal is to find the best dose and see if iExosomes can help treat this type of pancreatic cancer.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Mesenchymal Stromal Cells-derived Exosomes with KRAS G12D siRNA
PhasePhase 1/Phase 2
Primary goalMaximum Tolerated Dose Determined by Dose Limiting Toxicity

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Maximum Tolerated Dose Determined by Dose Limiting Toxicity, Overall survival (OS), Progression-free survival (PFS)

Body systems

Oncology