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Study details
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Etelcalcetide Trial in Children with Kidney Disease

Amgen
NCT IDNCT03633708ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

56

Study length

about 9.8 years

Ages

0–18

Locations

10 sites in CA, CO, MO +6

About this study

Researchers are testing a treatment called Etelcalcetide in children with kidney disease and high parathyroid hormone levels. This treatment aims to help manage these conditions, which can cause bone problems and other complications. The trial will last for about 3 years.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Etelcalcetide
PhasePhase 3
DrugEtelcalcetide
Routeinjection
Primary goalPercentage Change from Baseline in Mean iPTH During the EAP

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

etelcalcetide

Drug routes

injection (Injection)

Endpoints

Primary: Percentage Change from Baseline in Mean iPTH During the EAP

Secondary: Change from Baseline in Diastolic Blood Pressure, Change from Baseline in Heart Rate, Change from Baseline in Systolic Blood Pressure, Change in Weight, Maximum Serum Concentration (Cmax) of Etelcalcetide, Mean Change from Baseline in Predialysis iPTH from Baseline during the EAP, Number of Participants who Experienced Adverse Events (AEs), Percentage Change from Baseline in Corrected Total Serum Ca from Baseline During the EAP

Body systems

Renal