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Study details
Enrolling now

Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD

NYU Langone Health
NCT IDNCT03667846ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

150

Study length

about 5.9 years

Ages

18–70

Locations

1 site in NY

About this study

Researchers are testing whether topiramate, a medication, helps people with both alcohol use disorder and post-traumatic stress disorder (PTSD). The trial will also investigate if certain genetic markers can predict how well someone responds to this treatment. It aims to understand how topiramate works in individuals with both conditions and identify factors that influence treatment success.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Placebo
  • 2.Take Topiramate
PhasePhase 2
DrugTopiramate
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

topiramate

Drug routes

oral (Oral Tablet)

Body systems

Psychiatry / Mental Health