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Study details
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Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

Wayne State University
NCT IDNCT03736382ClinicalTrials.gov data as of Apr 2026
Target enrollment

40

Study length

about 7 years

Ages

18–60

Locations

2 sites in MI

About this study

This trial is testing if repeated daily exposure to mild intermittent hypoxia, combined with CPAP, can improve sleep apnea. The goal is to see if this approach helps reduce the need for CPAP and improves overall health.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Continuous positive airway pressure (CPAP)
  • 2.Mild intermittent hypoxia
  • 3.Sham protocol
Primary goalChange in blood pressure measured during quiet wakefulness over the 24 hour period following mild intermittent hypoxia and sham protocol

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change in blood pressure measured during quiet wakefulness over the 24 hour period following mild intermittent hypoxia and sham protocol

Secondary: Change in beat to beat measures of blood pressure following mild intermittent hypoxia and sham protocol, Change in blood pressure measured during sleep over 24 hours following mild intermittent hypoxia and sham protocol

Devices

therapeutic

Body systems

Neurology