Study details
Enrolling now
Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk
Icahn School of Medicine at Mount Sinai
NCT IDNCT03781765ClinicalTrials.gov data as of Apr 2026
Phase
Phase 4
Target enrollment
44
Study length
about 6.3 years
Ages
7–12
Locations
1 site in NY
About this study
This trial is testing whether stimulant or non-stimulant medications for ADHD affect brain reward systems in children who are not currently taking medication. Researchers will use fMRI to see how these treatments impact the brain's response to rewards.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Atomoxetine
- 2.Take Methylphenidate
PhasePhase 4
DrugAtomoxetine
Routeoral
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low7%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug classes
atomoxetine, methylphenidate (CNS stimulant; blocks reuptake of dopamine and norepinephrine)
Drug routes
oral (Oral Capsule), oral (Disintegrating Oral Tablet)
Body systems
Psychiatry / Mental Health