Deep Brain Stimulation Trial for Chronic Pain
16
about 6.2 years
40–75
2 sites in CA, TX
About this study
Researchers are testing deep brain stimulation of the subgenual cingulate cortex as a treatment for chronic, medically refractory low back pain. The trial will use a randomized, double-blind crossover design to evaluate its feasibility and preliminary effectiveness.
Based on ClinicalTrials.gov records.
What participants do
- 1.Use Deep Brain Stimulation of the Subgenus Cingulate Cortex
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Primary: At least 10% of study participants to experience one or more significant adverse events (SAEs), Change in at least 50% in pain scores on the Pain Anxiety Symptoms Scale -- Short Form 20 (PASS SF-20) compared to baseline., Change of at least 50% in pain scores on the visual analog scale (VAS) compared to baseline.
Secondary: 50% improvement in McGill Pain Questionnaire (MPQ), Change in EuroQol 5-Domain (EQ-5D) Score, Change in Montreal Cognitive Assessment Score (MoCA), Change in Short-Form 36 (SF-36) quality of life questionnaire score., Change in the Hamilton Depression Rating Scale (HAM-D), Change in the NIH Pain Intensity Survey, Change in the NIH Toolbox Pain Interference Computer Adaptive Test (CAT), Change in the PROMIS Pain Behavior CAT
implantable