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Study details
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Effects of Ketosis on Brain Function in Patients With T1DM

Boston Children's Hospital
NCT IDNCT04219709ClinicalTrials.gov data as of Apr 2026
Target enrollment

24

Study length

about 6.6 years

Ages

18–40

Locations

1 site in MA

About this study

This trial is testing whether a very low carbohydrate diet, which causes ketosis, affects brain function in people with type 1 diabetes. The goal is to understand how ketones protect the brain during periods of low blood sugar (hypoglycemia).

Based on ClinicalTrials.gov records.

What participants do

  • 1.Standard carbohydrate diet
  • 2.Very low carbohydrate diet

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Blood glucose level at which participant reports symptoms of hypoglycemia., Hypoglycemia symptoms

Body systems

Endocrinology