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Study details
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EMPOWER Trial

University of Southern California
NCT IDNCT04333706ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

65

Study length

about 6.9 years

Ages

18–99

Locations

3 sites in CA, FL

About this study

This trial is testing a new treatment called Sarilumab plus Capecitabine in people with triple-negative breast cancer. The goal is to see if it can help eliminate minimal residual disease (MRD) after standard treatments, potentially improving survival and cure rates for this aggressive type of breast cancer.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Capecitabine
  • 2.Take Sarilumab 150mg or 200 mg plus Capecitabine
  • 3.Take Sarilumab 150mg plus Capecitabine
PhasePhase 1/Phase 2
DrugCapecitabine
Routeoral
Primary goalPhase I: Dose-limiting toxicity (DLT)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

capecitabine, sarilumab, ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Phase I: Dose-limiting toxicity (DLT), Phase I: Maximum Tolerated Dose (MTD)

Body systems

Oncology