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Study details
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A Study of AZD0486 for B-Cell Non-Hodgkin Lymphoma

AstraZeneca
NCT IDNCT04594642ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

317

Study length

about 7.1 years

Ages

18–130

Locations

10 sites in FL, KY, NC +6

About this study

This trial is testing the safety and how well AZD0486 works in people with B-cell non-Hodgkin lymphoma. AZD0486 is a type of drug given through an IV infusion.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive AZD0486 IV
PhasePhase 1
Routeinfusion
Primary goalApparent terminal half-life (t1/2) of AZD0486

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug routes

infusion

Endpoints

Primary: Apparent terminal half-life (t1/2) of AZD0486, Incidence of subjects with Dose-limiting toxicities (DLT), Incidence of subjects with adverse events (AEs) and/or serious adverse events (SAEs), Maximum Observed Serum Concentration of AZD0486 (Cmax)

Secondary: Anti-Lymphoma Activity by Duration of Objective Response (DOR), Anti-Lymphoma Activity by Objective Response Rate (ORR), Anti-Lymphoma Activity by Progression-Free Survival (PFS)

Body systems

Oncology