Study details
Enrolling now
Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)
Johns Hopkins University
NCT IDNCT04601038ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
52
Study length
about 5.5 years
Ages
55+
Locations
1 site in MD
About this study
Researchers are testing if a medication called CORT108297 can help reduce the negative effects of stress on memory. The trial will involve people with mild cognitive impairment due to Alzheimer's disease and those at risk for developing Alzheimer's, who will receive either CORT108297 or a placebo over 10 weeks. Researchers will measure their cognitive performance before and after treatment.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take CORT108297
- 2.Take Placebo
PhasePhase 2
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low12%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Body systems
Neurology