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Study details
Enrolling now

RA-PRO PRAGMATIC TRIAL

University of Alabama at Birmingham
NCT IDNCT04692493ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

924

Study length

about 7.3 years

Ages

18+

Locations

48 sites in AL, AZ, CA +15

About this study

Researchers are testing whether switching to a non-TNFi biologic or a targeted synthetic DMARD (tsDMARD) improves patient-reported outcomes in people with active rheumatoid arthritis who are already taking a TNFi-biologic. The trial will compare these two treatment options to each other and to continuing the current TNFi-biologic treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take non-TNFi-biologic class
  • 2.Take targeted synthetic DMARD class
PhasePhase 3

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Body systems

Immune