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Study details
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Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease

Baylor College of Medicine
NCT IDNCT04740580ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

52

Study length

about 4.9 years

Ages

55–85

Locations

1 site in TX

About this study

Researchers are testing whether supplementing glycine and N-acetylcysteine or alanine as a placebo affects brain metabolism, inflammation, and cognition in people with Alzheimer's disease. The trial will last for 1780 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Alanine
  • 2.Glycine
  • 3.N-acetylcysteine
PhaseEARLY_Phase 1
DrugAlanine
Routeoral
Primary goalCognition

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

Therapeutic Nutrients/Minerals/Electrolytes (Biological Macromolecular Activity), glycine, acetylcysteine

Drug routes

oral (Oral Capsule)

Endpoints

Primary: Cognition

Secondary: Activities of daily living

Body systems

Neurology