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Study details
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Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

Supernus Pharmaceuticals, Inc.
NCT IDNCT04781140ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

286

Study length

about 1.8 years

Ages

4–5.75

Locations

47 sites in AL, AR, CA +21

About this study

This trial is testing a treatment called SPN-812 in children aged 4 to 5 years old who have ADHD. The goal is to see if this treatment helps with their symptoms and whether it's safe for them.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take 100mg SPN-812
  • 2.Take Placebo
PhasePhase 4
Primary goalChange from Baseline in the Attention-Deficit/Hyperactivity Disorder Rating Scale, 4th Edition, Preschool Version (ADHD-RS-IV-P) Total Score at End of Study (Week 6)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change from Baseline in the Attention-Deficit/Hyperactivity Disorder Rating Scale, 4th Edition, Preschool Version (ADHD-RS-IV-P) Total Score at End of Study (Week 6)

Secondary: Attention-Deficit/Hyperactivity Disorder Rating Scale, 4th Edition, Preschool Version (ADHD-RS-IV-P) Responder Rate (percentage of subjects with ≥ 50% Reduction in Change from Baseline) at End of Study (Week 6), Change from Baseline in Attention-Deficit/Hyperactivity Disorder Rating Scale, 4th Edition, Preschool Version (ADHD-RS-IV-P) Hyperactivity/Impulsivity Subscale Score at End of Study (Week 6), Change from Baseline in Attention-Deficit/Hyperactivity Disorder Rating Scale, 4th Edition, Preschool Version (ADHD-RS-IV-P) Inattention Subscale Score at End of Study (Week 6), Change from Baseline in the Clinical Global Impression of Severity (CGI-S) Score at End of Study (Week 6)

Body systems

Psychiatry / Mental Health