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Study details
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A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer

Edgewood Oncology Inc.
NCT IDNCT04872166ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

112

Study length

about 6 years

Ages

18+

Locations

6 sites in FL, OH, TN +1

About this study

Researchers are testing a treatment called BTX-A51 to see if it's safe, how well it works, and what the best dose might be. The trial will involve people with advanced solid tumors or breast cancer. It will happen in three phases: Phase 1a to find the right dose, Phase 1b to see if it works alone, and Phase 1c to test it when combined with another medication.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take BTX-A51
PhasePhase 1
Primary goalDefining the maximum tolerated dose (MTD) or recommended Phase 2 dose (RP2D) of BTX-A51alone and in combination with fulvestrant

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Defining the maximum tolerated dose (MTD) or recommended Phase 2 dose (RP2D) of BTX-A51alone and in combination with fulvestrant, Incidence of adverse events after BTX-A51 administration alone and in combination with fulvestrant

Secondary: Duration of response (DoR), Half-life of BTX-A51, Objective response rate (ORR), Overall survival (OS), Progression free survival (PFS)

Body systems

Oncology