Repurposing Low-Dose Clonidine for PTSD in Veterans
Phase 3
32
about 2.8 years
18+
1 site in WI
About this study
This trial is testing whether low-dose clonidine helps veterans with PTSD. It compares clonidine to a placebo pill over 1034 days. The goal is to see if the treatment improves PTSD symptoms, including daytime and nighttime issues.
Based on ClinicalTrials.gov records.
What participants do
- 1.Placebo
- 2.Take Clonidine Pill
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
CARDIOVASCULAR SYSTEM
oral
Primary: Change from Baseline in Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) questions B2 and E6 at 6 weeks into phase, Change from Baseline in PTSD Checklist-Military Version (PCL-5) at 6 weeks into phase, Change from Baseline in Pittsburgh Sleep Quality Index (PSQI) at 6 weeks into phase
Secondary: Change from Baseline in Patient Health Questionnaire (PHQ9) at 6 weeks into phase, Change from Baseline in Sleep Diary at 6 weeks into phase, Change from Baseline in quality of life scale (Q-LES-Q-SF) at 6 weeks into phase
Psychiatry / Mental Health