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Study details
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Twin Block, Pain Medications and Third Molar Extractions

Rutgers, The State University of New Jersey
NCT IDNCT04880707ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

48

Study length

about 2.5 years

Ages

18+

Locations

1 site in NJ

About this study

Researchers are testing whether a Twin block dental anesthetic injection can help manage pain after wisdom tooth removal. The trial will compare the Twin block to a placebo in patients experiencing significant jaw pain. Researchers will track pain levels and opioid usage over 7 days to see if the Twin block reduces pain and medication needs.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Twin block local anesthetic nerve block using standard dental anesthetic
  • 2.Twin block with placebo
PhasePhase 2
Primary goalMean NRS pain score

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low6%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Mean NRS pain score, Post-injection muscle pain