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Study details
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Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety

Massachusetts General Hospital
NCT IDNCT04912531ClinicalTrials.gov data as of Apr 2026
Target enrollment

80

Study length

about 2.7 years

Ages

18+

Locations

1 site in MA

About this study

This trial is testing a new way to help reduce pain and anxiety after heart surgery. It uses virtual reality, smells, and other devices to try and make patients feel better instead of using opioids or benzodiazepines. The goal is to see if this approach works and can be used in the future.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Use Bedside Olfaction Device
  • 2.Use Essence Olfactory Necklace
  • 3.Use Virtual Realty using a Microsoft Hololens, Empatica HR wristband, and EEG

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low4%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Change in Anxiety Score (State Trait Anxiety Inventory), Change in Pain Score (Visual Analogue Scale), Change in Quality of Life (The Functional Assessment of Cancer Therapy - General )(FACT-G), Change in Sleep Quality (Pittsburgh Sleep Quality Index), Change in Symptom Burden (Edmonton Symptom Assessment Scale), Patient satisfaction with the VR/OS system.

Devices

diagnostic

Body systems

Psychiatry / Mental Health