Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer
Phase 2
224
about 6.1 years
18–100
5 sites in GA, MD, NY +1
About this study
This trial is testing if atorvastatin can reduce hearing loss in people with head and neck cancer who are treated with cisplatin. Participants will take either atorvastatin or a placebo for a period of time, and their hearing will be monitored regularly to see if the medication helps prevent or lessen hearing loss.
Based on ClinicalTrials.gov records.
What participants do
- 1.Placebo
- 2.Take Atorvastatin
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
atorvastatin (Statin; inhibits HMG-CoA reductase to lower cholesterol)
oral
Secondary: To compare the incidence of grade (Bullet)3 AEs through 4 weeks after CRT with atorvastatin versus placebo., To examine the extent to which atorvastatin 40 mg alters overall survival and disease-free survival.
Oncology