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Study details
Enrolling now

PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD

Enrico Novelli
NCT IDNCT04925492ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

20

Study length

about 5.1 years

Ages

18+

Locations

1 site in PA

About this study

This trial is testing a new way to see vaso-occlusion, which is blood vessel blockage, in people with sickle cell disease. The goal is to find objective markers for VOC using positron emission tomography (PET). This will help improve patient care by showing when and how VOCs occur, as well as aid future drug research.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Positron Emission Tomography
  • 2.Take Cu-64]-LLP2A
PhasePhase 1
Primary goalAssociation of PET tracer uptake with intensity of pain in VOC

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Association of PET tracer uptake with intensity of pain in VOC

Procedures

imaging