Study details
Enrolling now
Clinical Effectiveness of the PICU Up! Multifaceted Early Mobility Intervention for Critically Ill Children
Johns Hopkins University
NCT IDNCT04989790ClinicalTrials.gov data as of Apr 2026
Target enrollment
1,440
Study length
about 3.6 years
Ages
≤18
Locations
11 sites in CA, FL, KY +8
About this study
Researchers are testing if a new intervention called PICU Up!, which includes goal-directed sedation, delirium prevention, sleep promotion, and family engagement, helps critically ill children breathe less support (mechanical ventilation) and improves their physical function compared to usual care. The trial will take place in many hospitals across the United States.
Based on ClinicalTrials.gov records.
What participants do
- 1.PICU Up!
Primary goalDuration of Mechanical Ventilation
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low3%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Endpoints
Primary: Duration of Mechanical Ventilation