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Study details
Enrolling now

Phase I/II Trial of NBTXR3 with Radiation and Immunotherapy

M.D. Anderson Cancer Center
NCT IDNCT05039632ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

40

Study length

about 2.7 years

Ages

18+

Locations

1 site in TX

About this study

This trial is testing a new treatment called NBTXR3, radiation therapy, and immunotherapy (Anti-PD-1/L-1) in people with advanced solid tumors that have spread to the lung or liver. The goal is to see if this combination can help control the disease.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Hafnium Oxide-containing Nanoparticles NBTXR3
  • 2.Receive Radiation Therapy
PhasePhase 1/Phase 2
Primary goalIncidence of dose limiting toxicities

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Incidence of dose limiting toxicities, Objective response rate

Procedures

radiation