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Study details
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Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Northwestern University
NCT IDNCT05042258ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

40

Study length

about 1.4 years

Ages

6–17

Locations

1 site in IL

About this study

Researchers are testing if dupilumab can improve sleep, reduce itching (pruritus), and help with circadian rhythm problems in children with moderate to severe atopic dermatitis. The trial will involve giving children dupilumab for 12 weeks and then having them undergo overnight sleep studies before and after treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Dupilumab
PhasePhase 4
DrugDupilumab
Primary goalPROMIS (Patient Reported Outcome Measurement Information System) parent-proxy score

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

dupilumab

Endpoints

Primary: PROMIS (Patient Reported Outcome Measurement Information System) parent-proxy score, PROMIS patient score

Body systems

Dermatology