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Study details
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MEM-288 Oncolytic Virus Trial

Memgen, Inc.
NCT IDNCT05076760ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

40

Study length

about 9.7 years

Ages

18+

Locations

2 sites in FL, NC

About this study

This trial is testing a new treatment, MEM-288, which is an oncolytic virus. It's being tested alone and in combination with standard cancer treatments like docetaxel and nivolumab to see if it can help people with advanced solid tumors.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive MEM-288 Intratumoral Injection
  • 2.Receive Nivolumab
  • 3.Take Docetaxel
PhasePhase 1
DrugDocetaxel
Routeinfusion
Primary goalPart 1A Monotherapy: Maximum Tolerated Dose (MTD)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

docetaxel, nivolumab (Immune checkpoint inhibitor; blocks PD-1 receptor on T cells)

Drug routes

infusion, injection

Endpoints

Primary: Part 1A Monotherapy: Maximum Tolerated Dose (MTD), Safety and Tolerability assessed by Adverse Events (AEs)

Secondary: Disease Control Rate (DCR), Overall Response Rate (ORR), Overall Survival (OS), Progression Free Survival (PFS)

Body systems

Oncology