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Study details
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A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery

Memorial Sloan Kettering Cancer Center
NCT IDNCT05130801ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

55

Study length

about 5 years

Ages

18+

Sex

Female only

Locations

2 sites in NJ, NY

About this study

Researchers are testing whether pre-operative mpMRI with additional sequences can improve surgical outcomes by providing more accurate information about the extent and acidity of the tumor than standard MRI. The trial also tests if using the fluorescent imaging agent pHLIP ICG during surgery, along with NIRF imaging, allows surgeons to see cancer cells in the tumor and nearby tissues more clearly and remove them completely.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Undergo pHLIP® ICG NIRF imaging
PhasePhase 1/Phase 2
Primary goalDose-limiting toxicity (DLT)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Dose-limiting toxicity (DLT)

Procedures

imaging

Devices

diagnostic

Body systems

Oncology