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Study details
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Sleep and Circadian Mechanisms in Hypertension

Oregon Health and Science University
NCT IDNCT05184933ClinicalTrials.gov data as of Apr 2026
Target enrollment

32

Study length

about 5.7 years

Ages

25–64

Locations

1 site in OR

About this study

This trial is testing how sleep and the body's natural clock affect blood pressure in people with high blood pressure. Investigators will trial participants with dipping and non-dipping hypertension. Participants will undergo various tests at home and in a lab to understand how sleep and circadian rhythms impact their blood pressure.

Based on ClinicalTrials.gov records.

What participants do

  • 1.At-home Polysomnography
  • 2.Circadian Protocol
  • 3.Overnight Sleep Trial
  • +2 more
Primary goalBlood pressure (Circadian and Overnight sleep vs. rested wakefulness trial)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Blood pressure (Circadian and Overnight sleep vs. rested wakefulness trial), Heart rate (Circadian and Overnight sleep vs. rested wakefulness trial), Heart rate variability (Circadian and Overnight sleep vs. rested wakefulness trial), Magnitude of overnight blood pressure dipping (Overnight sleep vs. rested wakefulness trial)

Secondary: Ambulatory blood pressure (Sleep regularization trial), Blood pressure dipping status (Sleep regularization trial)

Body systems

Cardiology / Heart