Examining the Effects of Estradiol on Neural and Molecular Response to Reward
Phase 4
103
about 4.7 years
45–55
Female only
1 site in NC
About this study
Researchers are testing whether estradiol, a hormone, affects brain function in women experiencing anhedonia (loss of interest), depression, or psychosis. The trial will use imaging techniques to see how estradiol impacts the brain's response to rewards.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Matching Placebo Patch
- 2.Take Micronized Progesterone
- 3.Take Raclopride C11
- +1 more
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers) (Progestational Hormone Receptor Agonists), estradiol
transdermal, oral (Oral Capsule), oral (Oral Tablet)
Secondary: Changes in PO Psychosis Symptoms following Estradiol Administration Using the BPRS
Psychiatry / Mental Health