Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
49
about 4.6 years
18–85
1 site in OH
About this study
Researchers are testing a new rehabilitation treatment for people with spinal cord injuries (SCI) to improve walking. The trial will measure certain features called biomarkers in blood and spinal fluid to determine the best time to start this training program. This training involves downhill treadmill walking with electrical stimulation, which helps practice walking even if full muscle control hasn't returned.
Based on ClinicalTrials.gov records.
What participants do
- 1.Downhill Eccentric Treadmill Training with Electrical Stimulation
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Primary: Change from baseline in electromyography of eccentric acting muscles, Change from baseline in kinematics during weight acceptance: ankle acceleration, Change from baseline in kinematics during weight acceptance: ankle range of motion, Change from baseline in kinematics during weight acceptance: hip acceleration, Change from baseline in kinematics during weight acceptance: hip range of motion, Change from baseline in kinematics during weight acceptance: knee acceleration, Change from baseline in kinematics during weight acceptance: knee range of motion, Change from baseline in kinetics during weight acceptance
Secondary: Change from 12 weeks to 16 weeks in 6 Minute Walk Test (6MWT), Change from 12 weeks to 16 weeks in Neuropathic Pain Symptom Inventory (NPSI) scale, Change from 12 weeks to 16 weeks in Numeric Pain Rating Scale (NPRS), Change from 12 weeks to 16 weeks on Neuromuscular Recovery Scale (NRS) score, Change from baseline in 10 Meter Walk Test, Change from baseline in 6 Minute Walk Test (6MWT), Change from baseline in ASIA Impairment Scale (AIS), Change from baseline in International Standards for Neurological Classification of SCI (ISNCSCI): motor scores
Neurology