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Study details
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Nitrous Oxide as Treatment for Fibromyalgia

University of Chicago
NCT IDNCT05357066ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

50

Study length

about 5.1 years

Ages

18–75

Locations

1 site in IL

About this study

Researchers are testing whether nitrous oxide can help reduce pain in people with fibromyalgia, a chronic condition causing widespread musculoskeletal pain. The trial will compare the effects of nitrous oxide to a placebo (an inactive substance).

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Nitrous oxide gas for inhalation
  • 2.Take Placebo
PhasePhase 2
DrugNitrous oxide gas for inhalation
Routeinhaled

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

anesthetic (Inhaled anesthetic gas; causes analgesia and mild anesthesia)

Drug routes

inhaled

Endpoints

Secondary: Hospital Anxiety and Depression Scale

Body systems

Musculoskeletal