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Study details
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Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

University of Texas Southwestern Medical Center
NCT IDNCT05358535ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

200

Study length

about 3.5 years

Ages

18+

Locations

1 site in TX

About this study

Researchers are testing two different mixtures of propofol and etomidate to see which one affects hemodynamics and causes fewer adverse events during anesthesia for endoscopic procedures. The trial will last 1289 days and involve approximately 200 adults.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)
  • 2.Take Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2)
PhasePhase 3
DrugAdmixture of propofol
Routeinjection
Primary goal% of cases with any oxygen saturation event below 85% by pulse oximetry

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low5%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

general anesthetic (Facilitates GABA; induces unconsciousness), NERVOUS SYSTEM

Drug routes

injection (Injection)

Endpoints

Primary: % of cases with any oxygen saturation event below 85% by pulse oximetry, Within treatment arm % of total group with a classic MACE event in the 30 days, Within treatment arm % of total group with a composite MACE event in the 30 days

Secondary: Within each treatment arm number of classic MACE events in the 30 days, Within each treatment arm number of composite MACE events in the 30 days