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Study details
Enrolling now

First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia

David Wilson
NCT IDNCT05374278ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

102

Study length

about 5.6 years

Ages

40–75

Locations

1 site in CA

About this study

Researchers are testing a new imaging agent, called [18F]RP-115, to see if it can help detect early changes in the brains of people with Alzheimer's disease or frontotemporal dementia. The trial will use PET/MRI or PET/CT scans.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take [18F]RP-115 PET/MRI or PET/CT and MRI
PhasePhase 1/Phase 2

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Body systems

Neurology