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Study details
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A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

Memorial Sloan Kettering Cancer Center
NCT IDNCT05412225ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

60

Study length

about 4 years

Ages

18+

Sex

Female only

Locations

7 sites in NJ, NY

About this study

This trial is testing a new way to treat breast cancer that involves giving radiotherapy before surgery and performing immediate reconstruction at the same time. The goal is to see if this approach is safe and feasible compared to the standard treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Neoadjuvant radiotherapy
  • 2.Undergo Pre-neoadjuvant radiotherapy (NART) biopsy
  • 3.Undergo Unilateral total mastectomy with axillary lymph node dissection
PhasePhase 1

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Procedures

radiation, surgery

Body systems

Oncology