Skip to content
Study details
Enrolling now

Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease

University of California, Los Angeles
NCT IDNCT05417555ClinicalTrials.gov data as of Apr 2026
Target enrollment

144

Study length

about 3.9 years

Ages

50–90

Locations

1 site in CA

About this study

Researchers are testing whether Low Intensity Focused Ultrasound Pulsation (LIFUP) can improve memory in people with Mild Cognitive Impairment and Mild Alzheimer's Disease. The trial will measure brain activity using MRIs and assess memory function through tests, while participants receive LIFUP treatment to a specific area of the brain involved in memory.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Use Low-Intensity Focused Ultrasound Pulsation (LIFUP)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Post-hoc biomarker analysis of APOE-4 status as a predictor of tFUS efficacy, Post-hoc biomarker analysis of plasma AB42/40 ratio as a predictor of tFUS efficacy, Post-hoc biomarker analysis of plasma ptau as a predictor of tFUS efficacy

Body systems

Neurology