Study details
Enrolling now
Extended Bolus for Meals in a Closed-loop System
University of California, San Francisco
NCT IDNCT05454891ClinicalTrials.gov data as of Apr 2026
Phase
Phase 4
Target enrollment
30
Study length
about 3.2 years
Ages
13–19
Locations
1 site in CA
About this study
This trial is testing whether giving more insulin at once (extended bolus) before meals, using a closed-loop system, can help control blood sugar levels better than standard insulin dosing. The goal is to see if the extended bolus helps prevent high or low blood sugar after eating.
Based on ClinicalTrials.gov records.
What participants do
- 1.Receive Extended bolus of insulin then standard bolus of insulin
- 2.Receive Standard bolus of insulin then extended bolus of insulin
PhasePhase 4
DrugExtended bolus of insulin then standard bolus of insulin
Routeinjection
Primary goalGlucose Area Under Curve [AUC]
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low8%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug routes
injection
Endpoints
Primary: Glucose Area Under Curve [AUC]
Body systems
Endocrinology