Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
Phase 2
90
about 9.9 years
65+
Female only
1 site in NC
About this study
Researchers are testing whether accelerated partial breast irradiation (APBI) alone, or endocrine therapy alone, after lumpectomy improves quality of life in older women with low-risk breast cancer. The trial will compare the effects of APBI and endocrine therapy on quality of life and disease control.
Based on ClinicalTrials.gov records.
What participants do
- 1.Receive Accelerated Partial Breast Irradiation (APBI)
- 2.Take tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
anastrozole, exemestane, fulvestrant, letrozole (Aromatase inhibitor; prevents estrogen production), tamoxifen (Selective estrogen receptor modulator (SERM); blocks estrogen in breast tissue), toremifene
oral (Oral Tablet), oral, injection
Primary: Patient reported outcomes assessed by EORTC QLQ-BR45, Patient reported outcomes assessed by European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ) C30
Secondary: Disease-free survival, Overall survival
radiation
Oncology