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Study details
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A Study Assessing KB407 for the Treatment of Cystic Fibrosis

Krystal Biotech, Inc.
NCT IDNCT05504837ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

12

Study length

about 2.6 years

Ages

18+

Locations

5 sites in FL, IL, NC +1

About this study

Researchers are testing a treatment called KB407, given through nebulization, to see if it's safe and well-tolerated in adults with cystic fibrosis. The trial will last approximately 946 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive KB407 (Nebulization)
PhasePhase 1
Primary goalTo evaluate safety and tolerability of KB407 based upon assessment of adverse events (frequency, severity, relatedness), and changes from baseline in physical examinations, vital signs, ECG, and clinical laboratory test results

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: To evaluate safety and tolerability of KB407 based upon assessment of adverse events (frequency, severity, relatedness), and changes from baseline in physical examinations, vital signs, ECG, and clinical laboratory test results

Secondary: To evaluate the effects of KB407 on pulmonary function, as measured by change from baseline in absolute and percent predicted FEV1

Body systems

Respiratory