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Study details
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Cardiac Rehabilitation for Building Exertional Heart Rate for Chronotropic Incompetence in Long COVID

University of California, San Francisco
NCT IDNCT05530317ClinicalTrials.gov data as of Apr 2026
Target enrollment

20

Study length

about 2.8 years

Ages

18+

Locations

1 site in CA

About this study

Researchers are testing if cardiac rehabilitation improves exercise capacity and how well your heart responds to exercise among people with Long COVID. The trial will include adults who have symptoms of Long COVID that last at least 3 months after the initial infection, along with reduced exercise capacity and a poor heart rate response during cardiopulmonary exercise testing.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Cardiac Rehabilitation
Primary goalChange in adjusted heart rate reserve

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change in adjusted heart rate reserve

Secondary: Change in Composite Autonomic Symptom Scale-31 (Compass 31) Score, Change in Generalized Anxiety Disorder Screener (GAD-7) Score, Change in Number of Long COVID symptoms, Change in Patient Health Questionnaire-9 (PHQ-9) Score, Change in Quality of life assessed with EuroQol (EQ-5D) Visual Analogue Scale, Change in Short Form Survey (SF-36) Score

Body systems

Infectious