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Study details
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Low Dose Naltrexone for Pain in Patients With HIV

Emory University
NCT IDNCT05537935ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

60

Study length

about 3.7 years

Ages

18–75

Locations

3 sites in GA

About this study

Researchers are testing whether low dose naltrexone can help reduce pain in people with HIV/AIDS. The trial will monitor CD4 counts as part of routine care to see if the medication improves immune function and reduces symptoms. This could be a new way to manage pain for people living with HIV.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Low Dose Naltrexone
PhasePhase 4
DrugLow Dose Naltrexone
Routeinjection
Primary goalChanges in Numerical Pain Score

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low12%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

NERVOUS SYSTEM

Drug routes

injection (Injection)

Endpoints

Primary: Changes in Numerical Pain Score

Secondary: Changes in Average pain Score, Changes in PROMIS pain Score

Body systems

Immune, Infectious