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Study details
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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

Chris Goss
NCT IDNCT05548283ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

730

Study length

about 3.6 years

Ages

6+

Locations

59 sites in AL, AZ, CA +29

About this study

This trial is testing whether a single aminoglycoside antibiotic, combined with a beta-lactam antibiotic, is as effective as two different antibiotics (tobramycin and a beta-lactam) in treating pulmonary exacerbations in people with cystic fibrosis. The goal is to determine if using one type of antibiotic provides the same improvement in lung function and symptoms compared to using two types.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Aminoglycoside
  • 2.Take Beta-lactam antibiotic
PhasePhase 4
DrugBeta-lactam antibiotic
Primary goalAbsolute Change in FEV1 % Predicted at Week 4 in Aminoglycoside (AG) Study

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

antibiotic

Endpoints

Primary: Absolute Change in FEV1 % Predicted at Week 4 in Aminoglycoside (AG) Study, Incidence of Adverse Events (AEs) in Aminoglycoside (AG) Study Intervention Arms

Body systems

Respiratory