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Study details
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CTX112 Trial

CRISPR Therapeutics AG
NCT IDNCT05643742ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

120

Study length

about 7 years

Ages

18+

Locations

4 sites in KS, MO, TX +1

About this study

This trial is testing the safety and effectiveness of CTX112 in people with relapsed or refractory B-cell malignancies. CTX112 is a type of immunotherapy that uses modified T cells to target cancer cells.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive CTX112
PhasePhase 1/Phase 2
Primary goalPhase 1 (Dose Escalation): Incidence of adverse events, defined as dose-limiting toxicities

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Phase 1 (Dose Escalation): Incidence of adverse events, defined as dose-limiting toxicities, Phase 2 (Cohort Expansion): Objective response rate

Secondary: Duration of Response, Overall Survival, Progression Free Survival

Body systems

Oncology