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Study details
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A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

Grifols Therapeutics LLC
NCT IDNCT05645107ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

386

Study length

about 3.5 years

Ages

18+

Locations

7 sites in CA, FL, MD +3

About this study

This trial is testing whether biweekly XEMBIFY® plus Standard Medical Treatment (SMT) will reduce the rate of major bacterial infections in people with B-cell CLL, MM, or NHL who have low antibody levels. Participants will receive either XEMBIFY® and SMT or a placebo and SMT for one year.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take Xembify
PhasePhase 3

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low12%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Body systems

Oncology