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Study details
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Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity

Columbia University
NCT IDNCT05655325ClinicalTrials.gov data as of Apr 2026
Target enrollment

144

Study length

about 2.6 years

Ages

55+

Locations

1 site in NY

About this study

Researchers are testing if 6 months of home-based walking improves memory, brain structure, and function in older adults with chronic kidney disease and mild cognitive impairment compared to health education. The trial will last for about a year.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Attention control
  • 2.Participate in Home-based walking exercise

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Change from baseline to 6-months in cerebral blood flow., Change from baseline to 6-months in hippocampal volume, Change from baseline to 6-months in white matter fractional anisotropy., Change from baseline to 6-months in white matter mean diffusivity.

Body systems

Neurology, Renal